Thursday 31 December 2015
Wednesday 30 December 2015
BEWARE TAMOF
Conditions associated with thrombocytopenia-associated multiple organ failure
| Cancer |
| Transplantation |
| Cardiovascular surgery/cardiopulmonary bypass |
| Autoimmune disease |
| Systemic infection |
| Vasculitis |
| Toxins |
| Cyclosporine A |
| FK 506 |
| Chemotherapy |
| Radiation |
| Ticlopidine |
| Hemolytic Uremic Syndrome variant syndromes |
DKA-FBC, BEWRE TAMOF-Thrombocytopenia-associated multi-organ failure (TAMOF) is an increasingly reported entity in the pediatric intensive care unit
Thrombocytopenia-associated multi-organ failure (TAMOF) is an increasingly reported entity in the pediatric intensive care unit
SPC=TAO
“I have just three things to teach:
Simplicity, patience, compassion.
These three are your greatest treasures.
Simple in actions and in thoughts,
You return to the source of being.
Patient with both friends and enemies,
You accord with the way things are.
Compassionate toward yourself,
You reconcile all beings in the world.”
Simplicity, patience, compassion.
These three are your greatest treasures.
Simple in actions and in thoughts,
You return to the source of being.
Patient with both friends and enemies,
You accord with the way things are.
Compassionate toward yourself,
You reconcile all beings in the world.”
— Lao Tzu, Tao Te Ching
The diagnoses most frequently cited in claims for adults were cancer and myocardial infarction and for children, meningitis.
The diagnoses most frequently cited in claims for adults were cancer and myocardial infarction and for children, meningitis.
Failure to or delay in diagnosis was the commonest misadventure cited in malpractice claims.
Failure to or delay in diagnosis was the commonest misadventure cited in malpractice claims.
Physicist Niels Bohr said: "There are trivial truths and great truths. The opposite of a trivial truth is plainly false. The opposite of a great truth is also true."
Physicist Niels Bohr said: "There are trivial truths and great truths. The opposite of a trivial truth is plainly false. The opposite of a great truth is also true."
that 34 percent of lethal prostate cancer would be reduced if all men exercised to the point of sweating for at least three hours a week,”
that 34 percent of lethal prostate cancer would be reduced if all men exercised to the point of sweating for at least three hours a week,”
CA PROSTATE RISK
One point was given for each of six behaviors:
not currently smoking or quitting smoking ten or more years ago,
body mass index under 30,
high vigorous physical activity,
high intake each of tomatoes and fatty fish, and
low intake of processed meat.
This gave a possible score of six points, three based on diet.
not currently smoking or quitting smoking ten or more years ago,
body mass index under 30,
high vigorous physical activity,
high intake each of tomatoes and fatty fish, and
low intake of processed meat.
This gave a possible score of six points, three based on diet.
EMO SPECTRUM
- Anger — Conspecific threat, trespass, loss attributed to an agent, unjust insult, thwarted goals, plea for justice
- Envy — Desiring other's stature objects
- Jealousy — Threat to sexual access.
- Fright — Concern for a future specific unpleasant event.
- Anxiety — Concern for an unidentified unpleasant event.
- Guilt — You have a standard and I did not meet it.
- Shame — I have a standard and I did not meet it
- Relief — Anticipated undesirable outcome has not occurred
- Hope — Anticipation of future desirable event or outcome
- Sadness — A specific undesirable outcome has occurred
- Depression — lost hope
- Happiness — A desirable event or outcome has occurred
- Pride — I approve of my actions, I have met a standard (mine = smug, yours = authentic)
- Love — Attraction and caring
- Gratitude — Appreciating another's kindness
- Compassion — Feeling the pain of another
- Aesthetic Experience — Awe, wonder, and slight fear of nature and its creations.
EVOLN OF JEALOUSY-Men who were indifferent to the potential sexual contacts between their wives and other men are not our ancestors” ~ Buss
Men who were indifferent to the potential sexual contacts between their wives and other men are not our ancestors” ~ Buss
Frequently when I cannot think because I feel fatigued, I have to eat something, for example cereals and fruits that are food with glucose.
Frequently when I cannot think because I feel fatigued, I have to eat something, for example cereals and fruits that are food with glucose.
during a tough self-control task, circulating glucose levels plummet, consumed by hardworking frontal neurons.
during a tough self-control task, circulating glucose levels plummet, consumed by hardworking frontal neurons.
WILLPOWER X GLUCOSE
carry out a particular behavior, the rate of glucose consumption jumps in the pertinent brain region. If you listen to a symphony, your auditory cortex elevates the metabolic rate. If you learn something new, it’s the hippocampus that fires up. Tap dancing sparks the motor cortex. And when you’re displaying willpower, thinking, “Don’t do it, don’t do it, you’ll regret it….” it’s your frontal cortex that kicks into gear.
ANXIOUS PPL ARE BETTER AT SOCIAL THREAT PERCEPTION
In a crowd, you will be most sensitive to an angry face looking towards you, and will be less alert to an angry person looking somewhere else.
“It is better to live your own destiny imperfectly than to live an imitation of somebody else’s life with perfection.” ― Anonymous, The Bhagavad Gita
“It is better to live your own destiny imperfectly than to live an imitation of somebody else’s life with perfection.”
― Anonymous, The Bhagavad Gita
“To be yourself in a world that is constantly trying to make you something else is the greatest accomplishment.” ― Ralph Waldo Emerson
“To be yourself in a world that is constantly trying to make you something else is the greatest accomplishment.”
― Ralph Waldo Emerson
And most of all pissed off that so many people feel TRAPPED in the rat race — feel doomed to work, work, work, buy a house, fill it with a bunch of crap, and die.
And most of all pissed off that so many people feel TRAPPED in the rat race — feel doomed to work, work, work, buy a house, fill it with a bunch of crap, and die.
Testing confirmed the modern Irish are descended from Stone Age people from the pre-biblical Middle East and migrants from southern Russia.
Testing confirmed the modern Irish are descended from Stone Age people from the pre-biblical Middle East and migrants from southern Russia.
MRI-When people decide to do things, the pre-motor cortex tends to light up just before other spots in the brain that control movement become
When people decide to do things, the pre-motor cortex tends to light up just before other spots in the brain that control movement become
ART INSTINCT CLUSTER CRITERIA
1/ DIRECT PLEASURE
2/SKILL AND VIRTUOSITY
3/STYLE
4/NOVELTY AND CREATIVITY
5/CRITICISM
6/REPRESENTATION
7/SPECIAL FOCUS
8/EXPRESSIVE INDIVIDUALITY
9/EMOTIONAL SATURATION
10/INTELLECTUAL CHALLENGE
11/ART TRADITIONS AND INTITUTIONS
12/IMAGINATIVE EXPERIENCE
2/SKILL AND VIRTUOSITY
3/STYLE
4/NOVELTY AND CREATIVITY
5/CRITICISM
6/REPRESENTATION
7/SPECIAL FOCUS
8/EXPRESSIVE INDIVIDUALITY
9/EMOTIONAL SATURATION
10/INTELLECTUAL CHALLENGE
11/ART TRADITIONS AND INTITUTIONS
12/IMAGINATIVE EXPERIENCE
SUBY-The risk of developing nonfatal cardiovascular disease (CVD) is nearly 2 times higher in patients who develop type 2 diabetes before age 40
The risk of developing nonfatal cardiovascular disease (CVD) is nearly 2 times higher in patients who develop type 2 diabetesbefore age 40
BMJOBIT-KOHNSON-consultant cardiologist Wessex Region, Southampton (b 1921; q Westminster Medical School, London, 1946; MD, FRCP), d 11 December 2015
consultant cardiologist Wessex Region, Southampton (b 1921; q Westminster Medical School, London, 1946; MD, FRCP), d 11 December 2015
“popularity effect.” The growing popularity of mindfulness means that outcomes may be influenced by participants’ belief that they are receiving a “fashionable” or proved psychotherapeutic technique
“popularity effect.” The growing popularity of mindfulness means that outcomes may be influenced by participants’ belief that they are receiving a “fashionable” or proved psychotherapeutic technique
arguments about belief in Hod as part of a tendency to want to control people and their minds.
arguments about belief in God or belief in science as part of a tendency to want to control people and their minds.
The real trouble with the multiverse is that it can’t be tested, not yet. We can’t put a telescope in the regions outside ours
The real trouble with the multiverse is that it can’t be tested, not yet. We can’t put a telescope in the regions outside ours
The ancients imbued the cosmos with consciousness and agency. The sun became a person, and so did the ocean
The ancients imbued the cosmos with consciousness and agency. The sun became a person, and so did the ocean
“All happy families are alike; each unhappy family is unhappy in its own way.” ― Leo Tolstoy, Anna Karenina
“All happy families are alike; each unhappy family is unhappy in its own way.”
― Leo Tolstoy, Anna Karenina
― Leo Tolstoy, Anna Karenina
Tuesday 29 December 2015
when our solar system was born 4.6 billion years ago only eight percent of the potentially habitable planets that will ever form in the universe existed.
when our solar system was born 4.6 billion years ago only eight percent of the potentially habitable planets that will ever form in the universe existed.
Meditation and mindfulness could help being in the moment – understanding that real ‘clock time’ is stable, and it is not really passing faster.”
Meditation and mindfulness could help being in the moment – understanding that real ‘clock time’ is stable, and it is not really passing faster.”
people who were always online tended to think an hour had passed when in fact it was only 50 minutes.
people who were always online tended to think an hour had passed when in fact it was only 50 minutes.
MEMORABLE PHOTOS-Conflict and suspense win — be it a pair of scissors in flight — or a man standing in front of a bear. Photos of bedrooms generally induce yawns.
Conflict and suspense win — be it a pair of scissors in flight — or a man standing in front of a bear. Photos of bedrooms generally induce yawns.
Combinations involving lack of physical activity, prolonged sitting, and poor sleep, as well as those involving smoking and high alcohol intake had the strongest associations with all-cause mortality.
Combinations involving lack of physical activity, prolonged sitting, and poor sleep, as well as those involving smoking and high alcohol intake had the strongest associations with all-cause mortality.
DM1 X GAD ab=Autoantibodies to the 65 kDa isoform of glutamate acid decarboxylase (GAD65Ab) are associated with a range of clinical disorders, including type 1 diabetes (T1D) and stiff-person syndrome (SPS).
Autoantibodies to the 65 kDa isoform of glutamate acid decarboxylase (GAD65Ab) are associated with a range of clinical disorders, including type 1 diabetes (T1D) and stiff-person syndrome (SPS).
VDD and insufficiency are common, even in Caucasians, at onset of T1D in pediatrics, worse in those with DKA.
VDD and insufficiency are common, even in Caucasians, at onset of T1D in pediatrics, worse in those with DKA.
vit d defy
vit d defy
Monday 28 December 2015
Term equivalent preterm infants spent significantly more time in a saturation range less than 90% compared to term infants. Feeding had no effect on saturation profile overall within each group.
Term equivalent preterm infants spent significantly more time in a saturation range less than 90% compared to term infants. Feeding had no effect on saturation profile overall within each group.
Among all physicians, obstetricians/gynecologists (ob/gyns) and surgeons are most likely to be sued, psychiatrists and pediatricians are least likely to be sued, and primary care physicians fall somewhere in between
Among all physicians, obstetricians/gynecologists (ob/gyns) and surgeons are most likely to be sued, psychiatrists and pediatricians are least likely to be sued, and primary care physicians fall somewhere in between
use of inhaled budesonide among premature infants appears to reduce development of BPD, but it may be associated with increased mortality.
use of inhaled budesonide among premature infants appears to reduce development of BPD, but it may be associated with increased mortality.
BMJOBIT-Theiham (b 1936; q BDS, University of Witwatersrand, 1957; PhD, DHC), died from mesothelioma on 24 November 2015.
heiham (b 1936; q BDS, University of Witwatersrand, 1957; PhD, DHC), died from mesothelioma on 24 November 2015.
Don’t listen to the news. “Think of how stupid the average person is, and realize half of them are stupider than that.” – George Carlin
Don’t listen to the news.
“Think of how stupid the average person is, and realize half of them are stupider than that.” – George Carlin
The brains of children with ASD have less of a neurotransmitter that helps people filter out competing stimuli.LESS GABA
The brains of children with ASD have less of a neurotransmitter that helps people filter out competing stimuli.LESS GABA
Saturday 26 December 2015
Late prematurity was associated with higher BMI and waist ratios in adolescence, but only the association with BMI was mediated by infant weight gain, suggesting vulnerability to metabolic risk in late premature births may arise through multiple pathways.
Late prematurity was associated with higher BMI and waist ratios in adolescence, but only the association with BMI was mediated by infant weight gain, suggesting vulnerability to metabolic risk in late premature births may arise through multiple pathways.
Our results provide strong support for lowering blood pressure to systolic blood pressures less than 130 mm Hg and providing blood pressure lowering treatment to individuals with a history of cardiovascular disease, coronary heart disease, stroke, diabetes, heart failure, and chronic kidney disease.
Our results provide strong support for lowering blood pressure to systolic blood pressures less than 130 mm Hg and providing blood pressure lowering treatment to individuals with a history of cardiovascular disease, coronary heart disease, stroke, diabetes, heart failure, and chronic kidney disease.
If you think adventure is dangerous, try routine. It is lethal. ~ Paulo Coelho
If you think adventure is dangerous, try routine. It is lethal. ~ Paulo Coelho 
HUMAN MIND FACULTIES
/////////////////INTUITIVE PHYSICS-how objects fall, bounce, bend
////////////////SENSE OF BIOLOGY- deep interest in plants, animals and strong feeling abt their species divsion
//////////////////INTUITIVE ENGG- eg flaking stones, attaching objects to one another
//////////////////PERSONAL PSYCHOLOGY-realise that others have minds like our own, but entertain different beliefs and intentions
////////////////INTUITIVE SENSE OF SPACE- a general mapping of the environment
//////////////////ABILITY TO READ FACIAL EXPRESIONS-sad, happy, angry,fear,surprise)
////////////////TENDENCY TO BODY ADORNMENT-paint, hairstyle, tatoo, jewelry
/////////////////FEELING OF PROBABILITY-also a capcity to track frequencies of events
//////////////////PRECISE ABY TO THROW OBJECTS AT A TARGET DISTANCE WITH CORRECT MOMENT OF HAND RELEASE- balls, rocks and spears
///////////////////SENSE OF MUSICALITY- fascination with organised pitched sounds,rhythmically produced by human voice or by instruments
////////////////////INTUITIVE ECONOMICS-sense of goods, favours, barters, fairness and reciprocity
/////////////////////SENSE OF JUSTICE-obligations, rights, revenge, what is derved, righteous anger
//////////////////////LOGICAL ABY -eg use of and,or, not,all, some, necessary,possible, cause
/////////////////////////SPONTANEOUS CAPACITY TO LEARN AND USE LANGG
////////////////SENSE OF BIOLOGY- deep interest in plants, animals and strong feeling abt their species divsion
//////////////////INTUITIVE ENGG- eg flaking stones, attaching objects to one another
//////////////////PERSONAL PSYCHOLOGY-realise that others have minds like our own, but entertain different beliefs and intentions
////////////////INTUITIVE SENSE OF SPACE- a general mapping of the environment
//////////////////ABILITY TO READ FACIAL EXPRESIONS-sad, happy, angry,fear,surprise)
////////////////TENDENCY TO BODY ADORNMENT-paint, hairstyle, tatoo, jewelry
/////////////////FEELING OF PROBABILITY-also a capcity to track frequencies of events
//////////////////PRECISE ABY TO THROW OBJECTS AT A TARGET DISTANCE WITH CORRECT MOMENT OF HAND RELEASE- balls, rocks and spears
///////////////////SENSE OF MUSICALITY- fascination with organised pitched sounds,rhythmically produced by human voice or by instruments
////////////////////INTUITIVE ECONOMICS-sense of goods, favours, barters, fairness and reciprocity
/////////////////////SENSE OF JUSTICE-obligations, rights, revenge, what is derved, righteous anger
//////////////////////LOGICAL ABY -eg use of and,or, not,all, some, necessary,possible, cause
/////////////////////////SPONTANEOUS CAPACITY TO LEARN AND USE LANGG
ZICA VIRUS- MICROCEPHALY
দেশ জুড়ে এমনই নির্দেশিকা জারি করেছে ব্রাজিলের স্বাস্থ্য মন্ত্রক। এ হেন আবেদনের কারণ— ‘জাইকা’ ভাইরাস। মশা-বাহিত ভাইরাসটি এক জনের দেহ থেকে ছড়িয়ে পড়ছে অন্যের দেহে। রেহাই পাচ্ছেন না অন্তঃসত্ত্বারাও। ফলে মায়ের থেকে ভাইরাসের সংক্রমণ ঘটছে সদ্যোজাত সন্তানের শরীরে। পরিণতি, ‘মাইক্রোসেফালি’,
V PRETERM INCR RISK OF ASD
“We were surprised by how many -- almost 30% -- of the extremely preterm-born children had developed ASD symptoms,” said Ulrika Ådén, MD, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden. “Amongst children born after full term pregnancy, the corresponding figure is 1%.”
People have known since the Stone Age that sugary liquids, given time, have a salutary tendency to ferment, transforming themselves into something like beer or wine
People have known since the Stone Age that sugary liquids, given time, have a salutary tendency to ferment, transforming themselves into something like beer or wine
The savanna hypothesis is the proposal that the major divergence between the hominins and other great apes was driven by hominins moving out of the forests and onto the grasslands.
The savanna hypothesis is the proposal that the major divergence between the hominins and other great apes was driven by hominins moving out of the forests and onto the grasslands.
FCKED BY ISBC STD VARIABLE MRTGG OVER TRACKER- 8 K LOSS -ACCPTED AND MV ON
SVR mortgages: advantages and disadvantages
 | When interest rates are low, your payments may go down |  | If interest rates go up, so will your payments. Even an increase of just 1% could add up to £83 a month to your repayments for a £100,000 mortgage |
| Arrangement fees for SVR mortgages tend to be lower than for trackers or fixed rates. There may be no arrangement fee charged at all | | Standard Variable Rates are not famed as the cheapest mortgage rates available, so you may be paying more than the best tracker or discounted rate mortgages around |
| There are generally no Early Repayment Charges, which allows for flexibility if you want to overpay, pay off the mortgage early, or remortgage to a new deal |
WHEN DOES COGN MISER KICK IN?
ALL THE TIME
ESP WHEN DECISION MAKER IS FATIGUED
ESP WHEN SLEEP DEPRIVED
ESP WHEN FEELING DOWN/DEPRESSED
ESP WHEN RESOURCES ARE LTD
DURING OVERCROWDING/LTD RESOURCES
ESP WHEN DECISION MAKER IS FATIGUED
ESP WHEN SLEEP DEPRIVED
ESP WHEN FEELING DOWN/DEPRESSED
ESP WHEN RESOURCES ARE LTD
DURING OVERCROWDING/LTD RESOURCES
DRS OUT OF TRAINING
SPEND MOST TIME IN SYTEM 1
MOST HEURISTICS AND BIASES ARE IN SYSTEM 1
MOST ERRORS OCCUR IN SYSTEM 1
REPETITIVE OPERATIONS OF SYSTEM 2 >>>1
SYSTEM2 OVERRIDE OF SYSTEM 1
SYSTEM 1 OVERRIDE OF SYSTEM 2
TOGGLE FN
COGNITIVE MISER FN- COMFORTABLY NUMB, PINK FLOYD
MOST HEURISTICS AND BIASES ARE IN SYSTEM 1
MOST ERRORS OCCUR IN SYSTEM 1
REPETITIVE OPERATIONS OF SYSTEM 2 >>>1
SYSTEM2 OVERRIDE OF SYSTEM 1
SYSTEM 1 OVERRIDE OF SYSTEM 2
TOGGLE FN
COGNITIVE MISER FN- COMFORTABLY NUMB, PINK FLOYD
A single oral dose of ondansetron, given before starting ORT to children UNDER 5 years of age with acute diarrhea and vomiting results in better oral rehydration.
A single oral dose of ondansetron, given before starting ORT to children <5 acute="" age="" and="" better="" diarrhea="" in="" nbsp="" of="" oral="" rehydration.="" results="" span="" vomiting="" with="" years="">
ED PED MED -DIFFICULT DECISION MAKING ENV
HI DECISION DENSITY
DECISION FATIGUE
THROUGHPUT PRESSURES
WIDE RANGE OF ILLNESSES
DXTIC UNCERTAINTY
NARROW TIME WINDOWS
INTERRUPTIONS AND DISTRACTIONS
SHIFT WORK/SLEEP DISRUPTION
SHIFT CHANGES
DECISION FATIGUE
THROUGHPUT PRESSURES
WIDE RANGE OF ILLNESSES
DXTIC UNCERTAINTY
NARROW TIME WINDOWS
INTERRUPTIONS AND DISTRACTIONS
SHIFT WORK/SLEEP DISRUPTION
SHIFT CHANGES
Landscape and longing
Savannah hypothesis
Habitat choice in the Pleistocene
Gatherer hunters on indefinite camping trip over thousands of generations
Human mind is crowded network of innate programs and routines
With growth of civilisation nature became wondrous and benign as depicted in art
Humans are born image makers and image enjoyers
Imitative play in child
Imitation is a natural process of enculturation of humans
Friday 25 December 2015
Thursday 24 December 2015
The scientific theory I like best is that the rings of Saturn are composed entirely of lost airline luggage." -- Mark Russell
The scientific theory I like best is that the rings of Saturn are composed entirely of lost airline luggage."
-- Mark Russell
-- Mark Russell
The legal system holds physicians to a high standard, and the penalties can be life altering for the involved clinician.
The legal system holds physicians to a high standard, and the penalties can be life altering for the involved clinician.
Physicians have active and time-consuming requirements for continuing medical education and board certification.
Physicians have active and time-consuming requirements for continuing medical education and board certification. Greater, than almost any profession.
Medicine is one of the most researched fields known to man. Billions are spent every year improving our clinical knowledge.
Medicine is one of the most researched fields known to man. Billions are spent every year improving our clinical knowledge.
Physicians are some of the most highly trained individuals in society. Our education is arduous and can span more than a decade.
Physicians are some of the most highly trained individuals in society. Our education is arduous and can span more than a decade.
A textbook presentation of a disease is very rare in clinical medicine. It happens infrequently
A textbook presentation of a disease is very rare in clinical medicine. It happens infrequently
Complications are not errors.
Complications are not errors. A small percentage of people who get colonoscopies will have the unfortunate complication of perforation
People die, for the most part, because they are sick.
People die, for the most part, because they are sick. Yes medical errors occur (even to healthy people). But medical errors happen more often in deathly ill, hospitalized patients, with poor prognoses to start with. The more ill the patient, the more complicated the care. More medicines. More tests. More risky procedures. More errors. This doesn’t mean that we must not strive to do better. But all those articles about how “hospitals kill more patients than …” are not genuine.
Wednesday 23 December 2015
GENE X LONGEVITY
cludedAPOE/TOMM40 (associated with Alzheimer’s disease), CDKN2B/ANRIL (implicated in the regulation of cellular senescence), ABO (tags the O blood group), and SH2B3/ATXN2 (a signaling gene that extends lifespan in Drosophila and a gene involved in neurological disease).
"Always borrow money from a pessimist. He won't expect it back." -- Oscar Wilde
"Always borrow money from a pessimist. He won't expect it back."
-- Oscar Wilde
-- Oscar Wilde
Happy Summer Solstice to 15% of all Humans and 100% of free Penguins who dwell in the Southern Hemisphere.TYSON
Happy Summer Solstice to 15% of all Humans and 100% of free Penguins who dwell in the Southern Hemisphere.TYSON
To achieve great things, two things are needed: a plan, and not quite enough time.
To achieve great things, two things are needed: a plan, and not quite enough time.
An unstable memory is in a privileged state: only when unstable can a memory communicate with and transfer knowledge to affect the acquisition of a subsequent memory.”
An unstable memory is in a privileged state: only when unstable can a memory communicate with and transfer knowledge to affect the acquisition of a subsequent memory.”
Tuesday 22 December 2015
the pre-hospital phase is acknowledged as a crucial period, when irreversible pathology and secondary injury to neuronal and cardiac tissue can be prevented.
the pre-hospital phase is acknowledged as a crucial period, when irreversible pathology and secondary injury to neuronal and cardiac tissue can be prevented.
Monday 21 December 2015
Sunday 20 December 2015
"Everything I like is either illegal, immoral or fattening."woolcott
"Everything I like is either illegal, immoral or fattening."woolcott
Saturday 19 December 2015
an increase in the rate of type 1 diabetes among children exposed to bereavement when exposure occurred after 11 years of age.
an increase in the rate of type 1 diabetes among children exposed to bereavement when exposure occurred after 11 years of age.
Friday 18 December 2015
Feel bad about things. You’re not supposed to be happy all the time.
Feel bad about things. You’re not supposed to be happy all the time.
home
If you are looking at buying a home as an “investment,” I strongly suggest you reconsider. For most of us, a house possesses all the worst qualities of an investment: it is illiquid, highly leveraged (usually), and drastically reduces the diversification of your portfolio. The tax benefits aren’t always as good as they sound. And if you are one of the people who believe that housing prices will always continue to go up, I have one word for you: bubble.
New open-label data from the expanded-access treatment program involving the cannabidiol Epidiolex (GW Pharma) show the median reduction in frequency of convulsive seizures after 3 months of treatment was 45% in all patients but higher in those with Dravet syndrome, among the most severe types of epilepsy.
New open-label data from the expanded-access treatment program involving the cannabidiol Epidiolex(GW Pharma) show the median reduction in frequency of convulsive seizures after 3 months of treatment was 45% in all patients but higher in those with Dravet syndrome, among the most severe types of epilepsy.
MCH WHO
Four Critical Pause Points
The checklist covers four "pause points" that occur at specific periods during a healthcare worker's normal workflow: (1) when the mother is admitted to the labor and delivery unit, (2) just before the woman begins to push or undergoes a cesarean delivery, (3) within 1 hour after birth, and (4) shortly before the mother and infant are discharged from the hospital.
Watching horror, or "bloodcurdling," movies is associated with an increase in the clotting protein, blood coagulant factor VIII,
Watching horror, or "bloodcurdling," movies is associated with an increase in the clotting protein, blood coagulant factor VIII,
Thursday 17 December 2015
SATAYU PROTECTION GENES
ABO Determines blood group
• CDKN2B Helps regulate cellular life cycles
• SH2B3 Has been shown to extend lifespan in fruit flies
• One of the HLA genes
black holes have eaten since the dawn of the universe, they argued, the greediest ones could have grown to a size of about 50 billion solar masses.
black holes have eaten since the dawn of the universe, they argued, the greediest ones could havegrown to a size of about 50 billion solar masses.
Aerodynamically, the bumble bee shouldn't be able to fly, but the bumble bee doesn't know it so it goes on flying anyway." -- Mary Kay Ash
Aerodynamically, the bumble bee shouldn't be able to fly, but the bumble bee doesn't know it so it goes on flying anyway."
-- Mary Kay Ash
-- Mary Kay Ash
Wednesday 16 December 2015
CA
When cancers evolve to the late stage of metastasis they are robust and equipped with genetic, or epigenetic, tricks that can thwart most cancer drugs.11 Given mutation rates, often enhanced by genetic instability, and the number of cells spawned—1012 or more—it is inevitable that rare cells will exist that are intrinsically drug resistant.
Cells have had three or more billion years to develop survival skills through random shuffling of their genomes—the substrate for all evolutionary change.
Cells have had three or more billion years to develop survival skills through random shuffling of their genomes—the substrate for all evolutionary change.
CA
As tumours expand, they solicit new blood supplies—angiogenesis—and become diffuse in the tissue of origin. In the face of increasing competition for space and resources, cells seek refuge elsewhere, by escaping into the blood circulation or lymphatics to establish residence as a diaspora in other tissues. Cancer then becomes a territorial hijack of essential tissue functions.
evo BRST CA
But if pregnancy is absent or delayed and breast feeding is not protracted (it is two to five years in hunter-gatherer societies), then each month between the ages of about 13-50 the breast (and ovary) receives a pulse of proliferative stress.
Homo sapiens. Our cancer rates are through the roof. It’s sometimes posited that this reflects the inevitable price of surviving into old age
Homo sapiens. Our cancer rates are through the roof. It’s sometimes posited that this reflects the inevitable price of surviving into old age
Tuesday 15 December 2015
Monday 14 December 2015
Drink your tea slowly and reverently, as if it is the axis on which the world earth revolves — slowly, evenly, without rushing toward the future. ~Thich Nhat Hanh
Drink your tea slowly and reverently, as if it is the axis on which the world earth revolves — slowly, evenly, without rushing toward the future. ~Thich Nhat Hanh
“Introverts love to reflect and process what’s going on — we like to be there and know we’re there,” explains Helgoe.
“Introverts love to reflect and process what’s going on — we like to be there and know we’re there,” explains Helgoe.
light swearing at the start or end of a persuasive speech can actually help influence an audience,
light swearing at the start or end of a persuasive speech can actually help influence an audience,
I don't want to earn a living; I want to live. ~ Oscar Wilde
I don't want to earn a living; I want to live. ~ Oscar Wilde 
Education is the most powerful weapon which you can use to change the world. - Nelson Mandela
Education is the most powerful weapon which you can use to change the world. - Nelson Mandela
it's greed, not money, that is the root of all evil. Money is nothing more than a medium of obtaining things and services
it's greed, not money, that is the root of all evil. Money is nothing more than a medium of obtaining things and services
extroverted (positive affectivity) temperament seems to be beneficial for language development.
extroverted (positive affectivity) temperament seems to be beneficial for language development.
NNJ X MASSAGE-IRN P
Massage group had a lower transcutaneous billirubin levels compared to the control group, thus, these pilot results indicate that massaging the newborns can be accompanied by a lower bilirubin level in the healthy term newborn.
HDMITE X GUT DYSFN
HDM, a ubiquitous environmental factor, is present in the human gut where it directly affects gut function through its proteolytic activity. HDM may be an important trigger of gut dysfunction and warrants further investigation.
Sunday 13 December 2015
"The best thing one can do when it's raining is to let it rain." longfellow
"The best thing one can do when it's raining is to let it rain." longfellow
"If you're naturally kind, you attract a lot of people you don't like."lether
If you're naturally kind, you attract a lot of people you don't like."lether
Meditation is not a means to an end it is both the means and the end. -J. Krishnamurti
Meditation is not a means to an end it is both the means and the end. -J. Krishnamurti
"Kids should be allowed to break stuff more often. That's a consequence of exploration. Exploration is what you do when you don't know what you're doing." -- Neil deGrasse Tyson
"Kids should be allowed to break stuff more often. That's a consequence of exploration. Exploration is what you do when you don't know what you're doing."
-- Neil deGrasse Tyson
-- Neil deGrasse Tyson
"Man loves company - even if it is only that of a small burning candle."LICHTENSTEIN
"Man loves company - even if it is only that of a small burning candle."LICHTENSTEIN
Saturday 12 December 2015
Look deep into nature, and then you will understand everything better." -- Albert Einstein
Look deep into nature, and then you will understand everything better."
-- Albert Einstein
-- Albert Einstein
In three words I can sum up everything I've learned about life: It goes on. ~ Robert Frost
In three words I can sum up everything I've learned about life: It goes on. ~ Robert Frost
I was once anti-biotic. But lately I've been more pro-biotic after reading more about their culture.TYSON
I was once anti-biotic. But lately I've been more pro-biotic after reading more about their culture. TYSON
Thursday 10 December 2015
dexamethasone can be considered an appropriate therapy for noncomplicated asthma in children requiring hospital admission and can be used in place of the more prevalent regimens of prednisone or prednisolone.
dexamethasone can be considered an appropriate therapy for noncomplicated asthma in children requiring hospital admission and can be used in place of the more prevalent regimens of prednisone or prednisolone.
among children hospitalized for anaphylaxis, the receipt of glucocorticoid in the ED was associated with a lower odds of a prolonged hospital stay. They suggest that the findings of this study support administration of glucocorticoids to children hospitalized for anaphylaxis.
among children hospitalized for anaphylaxis, the receipt of glucocorticoid in the ED was associated with a lower odds of a prolonged hospital stay. They suggest that the findings of this study support administration of glucocorticoids to children hospitalized for anaphylaxis.
"Azithromycin therapy decreased the overall severity of symptoms during severe LRTIs compared with placebo, as reflected by lower mean total symptom scores over the duration of RTI, but not during episodes not progressing to severe LRTI,
"Azithromycin therapy decreased the overall severity of symptoms during severe LRTIs compared with placebo, as reflected by lower mean total symptom scores over the duration of RTI, but not during episodes not progressing to severe LRTI,
nothing is more important than to experience other cultures and discover how many ways humans have discovered to live.
nothing is more important than to experience other cultures and discover how many ways humans have discovered to live.
Don't surrender your loneliness so quickly. Let it cut more deep. Let it ferment and season you. As few human or even divine ingredients can. ~Hafiz
Don't surrender your loneliness so quickly. Let it cut more deep. Let it ferment and season you. As few human or even divine ingredients can. ~Hafiz 
Introversion has nothing to do with shyness or general awkwardness; it is an inbuilt aversion to high stimulation environments – lots of noise, lots of people and bright lights,
Introversion has nothing to do with shyness or general awkwardness; it is an inbuilt aversion to high stimulation environments – lots of noise, lots of people and bright lights,
Wednesday 9 December 2015
In times of great stress or adversity, it's always best to keep busy, to plow your anger and your energy into something positive." -- Lee Iacocca
In times of great stress or adversity, it's always best to keep busy, to plow your anger and your energy into something positive."
-- Lee Iacocca
-- Lee Iacocca
But I'll tell you what hermits realize. If you go off into a far, far forest and get very quiet, you'll come to understand that you're connected with everything. ~ Alan Watts
But I'll tell you what hermits realize. If you go off into a far, far forest and get very quiet, you'll come to understand that you're connected with everything. ~ Alan Watts 
Tuesday 8 December 2015
Monday 7 December 2015
"Life is all about the little decisions you make everyday. You can't change the decisions of the past, but every new day is another opportunity to make the right ones." -- Author Unknown
"Life is all about the little decisions you make everyday. You can't change the decisions of the past, but every new day is another opportunity to make the right ones."
-- Author Unknown
-- Author Unknown
You don’t owe anyone another excuse (but you owe yourself another chance).
You don’t owe anyone another excuse (but you owe yourself another chance).
Simple febrile seizures tend to occur early in the illness within 24hrs of onset of fever – if the seizure occurs >24hrs after the onset of fever, the suspicion for a bacterial cause of the fever and a pathologic cause for the seizure should be heightened.
Simple febrile seizures tend to occur early in the illness within 24hrs of onset of fever –
if the seizure occurs >24hrs after the onset of fever, the suspicion for a bacterial cause of the fever
and a pathologic cause for the seizure should be heightened.
TRUE SZOR OR SZR MIMIC
Elements that are highly suggestive of true seizure activity include:
- Lateralized tongue-biting (high specificity)
- Flickering eye-lids
- Dilated pupils with blank stare
- Lip smacking
- Increased heart rate and blood pressure during event
- Post-ictal phase
People with temporal epilepsy caused by hippocampal sclerosis (TLE-HS) have impaired memory and find it particularly challenging to recall details of specific events in everyday life.
People with temporal epilepsy caused by hippocampal sclerosis (TLE-HS) have impaired memory and find it particularly challenging to recall details of specific events in everyday life.
hippocampus is memory, its loss is memory loss
hippocampus is memory, its loss is memory loss
The SCN8A gene mediates electrical signaling in the brain by controlling the flow of sodium currents
The SCN8A gene mediates electrical signaling in the brain by controlling the flow of sodium currents
channelopathy gene panel
channelopathy gene panel
Sunday 6 December 2015
epigenetics-What your father ate before you were born could influence your health
What your father ate before you were born could influence your health
"Learn to enjoy every minute of your life. Be happy now. Don't wait for something outside of yourself to make you happy in the future. Think how really precious is the time you have to spend, whether it's at work or with your family. Every minute should be enjoyed and savored." -- Earl Nightingale
"Learn to enjoy every minute of your life. Be happy now. Don't wait for something outside of yourself to make you happy in the future. Think how really precious is the time you have to spend, whether it's at work or with your family. Every minute should be enjoyed and savored."
-- Earl Nightingale
-- Earl Nightingale
Saturday 5 December 2015
For Freud, belief in hod was a neurotic regression to childhood, with Hod representing an omnipotent father figure
For Freud, belief in Hod was a neurotic regression to childhood, with Hod representing an omnipotent father figure
HOD-the ‘consolationist’ approach maintains that religion consoles human beings against our mortality and the sheer hardship and suffering which fills our lives (Boyer, 2002).
HOD-the ‘consolationist’ approach maintains that religion consoles human beings against our mortality and the sheer hardship and suffering which fills our lives (Boyer, 2002).
HOD-‘intellectualist’ approach suggests that human beings invented gods and the religions associated with them to explain the world.
HOD-‘intellectualist’ approach suggests that human beings invented gods and the religions associated with them to explain the world.
The richest 10% of people produce half of Earth’s climate-harming fossil-fuel emissions, while the poorest half contribute a mere 10%,
The richest 10% of people produce half of Earth’s climate-harming fossil-fuel emissions, while the poorest half contribute a mere 10%,
If you are born on Tuesday, not only will you be full of grace, but you will also be more likely to survive than if you are born on a Thursday.
If you are born on Tuesday, not only will you be full of grace, but you will also be more likely to survive than if you are born on a Thursday.
Quote-sometimes the only possible way to take away all your pain is to give you so much medication you stop breathing reliably
sometimes the only possible way to take away all your pain is to give you so much medication you stop breathing reliably- quote
A person who starts kindergarten at age 5, graduates at 18, finishes college at 22 and med school at 26 can finish residency and be a fully licensed/practicing physician at the ripe old age of 29 years old.
A person who starts kindergarten at age 5, graduates at 18, finishes college at 22 and med school at 26 can finish residency and be a fully licensed/practicing physician at the ripe old age of 29 years old.
(Insider tip for non-emergencies: show up around 6 a.m.on morning and you probably won’t have to wait
(Insider tip for non-emergencies: show up around 6 a.m.on morning and you probably won’t have to wait
Wait times in most emergency departments are ridiculous. But, if you have a real emergency, you won’t have to wait.
Wait times in most emergency departments are ridiculous. But, if you have a real emergency, you won’t have to wait.
Parental Absence Alters Children’s Brain Development
Left-behind children had more gray matter in areas of the brain related to memory and the emotions.
The researchers think this may be a result of insufficient pruning of synapses, the connections between neurons.
Synaptic pruning is thought to be a vital developmental stage in adolescence.
Children who had higher gray matter volume in these areas tended to have lower IQs, the researchers found.
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