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Although we often talk of the
amygdala and hippocampus as being single structures, there are actu-
ally two parts to each, one half in each hemisphere of your brain.
• Amygdala: Your brain’s alarm center. It senses threats and
other emotionally significant information and initiates the
stress response.
• Hypothalamus: Your brain’s operations manager. It coordi-
nates the release of stress hormones to ready your body for
fighting or fleeing.
• Hippocampus: Your brain’s biographer. It stores and retrieves
conscious memories about the current situation as well as
Your Brain’s Stress Response 15
previous stressors you’ve experienced, how you responded,
and resulting outcomes. This allows you to learn from past
experience and anticipate what’s likely to happen.
• Prefrontal cortex: Your brain’s CEO. It puts together infor-
mation from your amygdala and hippocampus to create a
planned, motivated response to stress. It communicates back
and forth with the amygdala to modify your response as the
stressor unfolds.
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