– The production of lactate actually consumes hydrogen ions. Lactic acidosis is really lactic alkalosis.
– Lactate is produced physiologically and is a precursor for gluconeogenesis.
– During exercise, skeletal muscle exports lactate as the primary fuel for the heart and brain.
– At VO2max, intracellular oxygen stays the same. Anaerobic metabolism in cells only occur as a pre-terminal event. The exception is in complete arterial occlusion.
– Adrenaline promotes lactate production
– Lactate infusion has been shown to increase cardiac output in septic and cardiogenic shock
– Lactate is a survival advantage!
– Lactate is produced physiologically and is a precursor for gluconeogenesis.
– During exercise, skeletal muscle exports lactate as the primary fuel for the heart and brain.
– At VO2max, intracellular oxygen stays the same. Anaerobic metabolism in cells only occur as a pre-terminal event. The exception is in complete arterial occlusion.
– Adrenaline promotes lactate production
– Lactate infusion has been shown to increase cardiac output in septic and cardiogenic shock
– Lactate is a survival advantage!
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