GALT X IMMUNITY

GALT development (which is influenced by intestinal microbes) must remain strong. Interestingly, the gut’s initial response to a substance is the same whether the substance is healthy or pathogenic; the microbiota, which influences GALT, is what determines whether the final response will be tolerogenic (producing immunological tolerance) or immunogenic (producing an immune response). In short, it is up to the GALT to inhibit the development of allergy or autoimmunity."