NICE says a tick bite and a circular red rash, known as erythema migrans, suggests a diagnosis of Lyme disease and should be treated with antibiotics without further testing. For patients who require antibody tests, a negative result accompanied by continued symptoms should be followed up by a second opinion from a specialist.

NICE says a tick bite and a circular red rash, known as erythema migrans, suggests a diagnosis of Lyme disease and should be treated with antibiotics without further testing. For patients who require antibody tests, a negative result accompanied by continued symptoms should be followed up by a second opinion from a specialist.