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Although it is difficult to disentangle the specific role of anhedonia in major depressive disorder, imaging studies have clearly shown that the severity of anhedonia is correlated, in depressed patients, with a deficit of activity of the ventral striatum (reflecting decreased function of the nucleus accumbens, probably as a primary event) and an excess of activity of ventral region of the prefrontal cortex (concerning an increased function of the VMPFC and the orbitofrontal cortex, probably as a secondary phenomenon).
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BOTTOM UP VIEW X BIG PICTURE
Eating walnuts can improve mood by 28 percent, research finds.
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“We used a validated questionnaire called Profiles of Mood States (POMS).
It is one of the most widely used and accepted mood scales in studies on cognition.
The test has six mood domains: tension, depression, anger, fatigue, vigor, confusion and also provides a Total Mood Disturbance score (TMD).
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Anita Sethi’s I Belong Here (2021), in which the author considers a blade of grass:
Can you imagine a blade of grass having low self-esteem, being made to hate its colour or shape? Despite being so literally trodden upon, it is so sure of itself, so confident in its skin. Be more like grass growing, I think.
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