FMT

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Fecal Microbiota Transplant (FMT) is the process of transferring stool from a healthy donor into the gut of a recipient to restore a balanced microbiome. It’s primarily used to treat recurrent Clostridioides difficile (C. diff) infections, which can be life-threatening and often resist antibiotics.

How It Works

🚽 Healthy stool is screened for pathogens and processed into a liquid or capsule form.
💉 Delivery methods:

• Colonoscopy (most common)

• Nasogastric/Nasoduodenal tube

• Enema

• Oral capsules (less invasive)

Why It Works

• Restores gut microbiome diversity

• Outcompetes harmful bacteria like C. diff

• May improve immune regulation

Beyond C. diff – Potential Uses (Still Experimental)

• Inflammatory Bowel Disease (IBD) (Crohn’s, Ulcerative Colitis)

• Irritable Bowel Syndrome (IBS)

• Metabolic disorders (Obesity, Diabetes)

• Neurological conditions (Autism, Depression, Parkinson’s)

Risks & Challenges

⚠️ Infection risk if screening isn’t thorough
⚠️ Unpredictable long-term effects
⚠️ Ethical & regulatory hurdles

FMT is a fascinating area of medicine, showing how gut bacteria can influence health far beyond digestion! 🚀