///////////////////ADHD Candidate Gene Study in a Population-Based Birth Cohort: Association with DBH and DRD2 Nyman, E.S., et al. - Attention-deficit/hyperactivity disorder (ADHD) is a common childhood-onset disorder with a significant impact on public health...Our study supports the involvement of the dopamine pathway in the etiology of ADHD; specifically the genes DBH and DRD2 deserve more attention in further studies [more...]
Journal of the American Academy of Child and Adolescent Psychiatry, 11/28/07
////////////////////Rheumatic Chorea: Relationship to Systemic Manifestations and Response to Corticosteroids Walker, A.R., et al. - To describe Sydenham chorea among children in a cohort of patients with rheumatic fever (RF)...Chorea affected one-third of the children with RF. Patients with chorea were less likely to have severe cardiac or rheumatologic complications of RF. Therapy with prednisone shortened the duration of rheumatic chorea; some reported recurrences of chorea and had minor neurologic sequelae [more...]
Journal of Pediatrics, 11/28/07
//////////////////////Disability in Adult Survivors of Childhood Cancer: A Swedish National Cohort Study Hjern, A., et al. - Childhood cancer survivors more often have persistent needs of supportive measures provided by community and/or the parental household. The survivors of CNS tumors were at particular risk, indicating a need of safer treatment protocols, and tailored follow-up, prevention, and rehabilitation to address this persistent social disability [more...]
Journal of Clinical Oncology, 11/21/07
///////////////////////Pediatric onset Crohn's colitis is characterized by genotype-dependent age-related susceptibility Levine, A., et al. - In early-onset pediatric CD, children with NOD2/CARD15 mutations demonstrate more ileocolitis and less isolated ileitis. Young children without NOD2/CARD15 mutations have an isolated colonic disease distribution, suggesting that this phenotype is associated with genes that lead to a specific phenotype of early-onset disease [more...]
Inflammatory Bowel Disease, 11/26/07
//////////////////////Serum and Glucocorticoid-Inducible Kinase in Pulmonary Tissue of Preterm Fetuses Exposed to Chorioamnionitis Wirbelauer, J., et al. - Human serine threonine kinase SGK1 mRNA is observed in fetal lung tissue. On the basis of this study, we speculate that exposure to chorioamnionitis is associated with a downregulation of SGK1 in fetal lung tissue. The possible consequences of a decreased rate of SGK1 mRNA could be an impaired ability to clear the lungs from excessive fluid immediately after preterm birth [more...]
Biology of the Neonate, 11/26/07
////////////////////Mutation of SBDS and SH2D1A is not associated with aplastic anemia in Japanese children Wang, Y., et al. - During the last decade, the genetic basis of inherited bone marrow failure syndromes has been identified. Recently, genetic factors predisposing to aplastic anemia (AA) have been found in a few patients with apparently acquired AA. Here we present the genetic analysis of SBDS and SH2D1A in Japanese children with AA [more...]
Haematologica, 11/16/07 Free Full Text
////////////////////Childhood Predictors of Young-Onset Type 2 Diabetes Franks, P.W., et al. - We have determined the relative value of the features of the metabolic syndrome in childhood for the prediction of subsequent type 2 diabetes. Our findings suggest that strategies targeting obesity, dysregulated glucose homeostasis, and low HDL cholesterol during childhood and adolescence may have the most success in preventing diabetes [more...]
Diabetes, 11/28/07
/////////////////////Now that I've been here in India for 6 months for the first time in almost 4 decades, I'm predisposed to voicing, in response to that statement, platitudes such as: "India is the world's biggest democracy, and it WORKS!" It sucks big-time, too, but much of the time, in SO MANY institutions, in so many ways, it bloody works. In particular, about letting others be -- others who think and eat and dress and pray differently -- they beat each other up and hack each other up and put stakes through each other's live fetuses, but they do this about 0.000001% of the time. The rest of the time they exist peacefully. AND they're becoming an economic (if polluted) giant on the world stage.There aren't too many societal success stories in history to equal present day India's.- AjitD
SASIALIT
//////////////////India's 'pink' vigilante women By Soutik Biswas BBC News, Banda The 'pink' gang has staged protests against corrupt officialsThey wear pink saris and go after corrupt officials and boorish men with sticks and axes. The several hundred vigilante women of India's northern Uttar Pradesh state's Banda area proudly call themselves the "gulabi gang" (pink gang), striking fear in the hearts of wrongdoers and earning the grudging respect of officials. The pink women of Banda shun political parties and NGOs because, in the words of their feisty leader, Sampat Pal Devi, "they are always looking for kickbacks when they offer to fund us". Two years after they gave themselves a name and an attire, the women in pink have thrashed men who have abandoned or beaten their wives and unearthed corruption in the distribution of grain to the poor. They have also stormed a police station and attacked a policeman after they took in an untouchable man and refused to register a case. Poorest "Nobody comes to our help in these parts. The officials and the police are corrupt and anti-poor. So sometimes we have to take the law in our hands. At other times, we prefer to shame the wrongdoers," says Sampat Pal Devi, between teaching a "gang" member on how to use a lathi (traditional Indian stick) in self defence.
/////////////////////BEFORE THE END If fate means you to lose, give him a good fight anyhow.William McFee Casuals Of The Sea It’s how you show up at the showdown that counts.Homer Norton (1896-1965)College football coach
FIND AT THE END=FATE
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