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Type 1 diabetes: target HbA1c for preventing retinopathy and microalbuminuria

In daily practice, in children and adults with type 1 diabetes, the relative risk (RR) of any incident retinopathy and microalbuminuria may be significantly lower when mean glycosylated haemoglobin (HbA1c) levels are maintained at:

Correct! The answer is B 

• A

  <6 .5="" 6.5-6.9="" div="" rather="" than="">
 
• 6.5-6.9% rather than 7.0-7.4%
 
• C

  Options A and B
 
• D

  None of the above

Commented answer

A study of the Swedish national registry analysed the long-term progression (12 years) of 10,400 diabetic children and adults (mean age 15 years) and found no significant reduction in the RR of incident retinopathy and microalbuminuria for HbA1c <6 .5="" 31="" 55="" 6.5-6.9="" 7.0-7.4="" and="" at="" compared="" episodes="" first="" frequent="" group.="" hba1c="" higher="" however="" hypoglycaemic="" in="" more="" p="" patients="" respectively="" rrs="" severe="" significantly="" the="" these="" those="" though="" to="" vs.="" was="" were="" whose="" with="">