BPLS SEPSIS Under 3 months old: add amoxicillin to cover Listeria. •Use cefotaxime (not ceftriaxone) in premature or jaundiced infants, in hypoalbuminaemia and if calcium infusion is being used. •If hospital acquired or neutropenic, consider tazobactam. •If previous culture of resistant organism, give appropriate antibiotic (e.g. methicillin-resistant Staphylococcus aureus (MRSA): add vancomycin; extended-spectrum β-lactamases (ESBL): meropenem). •If vascular access device has been used for more than 48 hours add vancomycin.

• Under 3 months old: add amoxicillin to cover Listeria.
• •Use cefotaxime (not ceftriaxone) in premature or jaundiced infants, in hypoalbuminaemia and if calcium infusion is being used.
• •If hospital acquired or neutropenic, consider tazobactam.
• •If previous culture of resistant organism, give appropriate antibiotic (e.g. methicillin-resistant Staphylococcus aureus (MRSA): add vancomycin; extended-spectrum β-lactamases (ESBL): meropenem).
• •If vascular access device has been used for more than 48 hours add vancomycin.