Dutch physiologist Hartog Jacob Hamburger invent as was subsequently referred to as “normal xxxxx“
- Saline
- During the late 1800 doctors were trying to treat cholera patients with intravenous fluids based on Thomas Latta’s work in 1832. Various mixtures of sodium, chloride, potassium and bicarbonate were used but haemolysis was common.
- Hamburger created a solution with 0.9% NaCl and observed no haemolysis to red blood cells incorrectly concluding this was the normal concentration in blood (its 0.6%) and hence the term “normal saline” was adopted. The solution is however, isotonic and therefore haemolysis does not occur.
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