EOL Psyd

 A

Absolutely. Here’s a clear table summarizing common protocols for psychedelic-assisted therapy at the end of life, including typical substances, dosage ranges, therapeutic setting, and session structure. This is drawn from clinical trials and research studies (e.g., Johns Hopkins, NYU, MAPS).

Substance	Typical Clinical Dose	Therapeutic Setting	Session Structure	Purpose / Expected Outcome
Psilocybin	20–30 mg (oral, ~0.3–0.5 mg/kg)	Comfortable room, often dim lighting, music	1–2 preparatory sessions, 1 supervised dosing session (6–8 hours), integration session afterward	Reduce anxiety/depression, facilitate acceptance of mortality, mystical/spiritual experiences, improved well-being
Ketamine	0.5–1 mg/kg IV or 50–100 mg IM/sub-lingual	Medical setting with monitoring	1–5 sessions over days/weeks, 40–60 min per session	Rapid-acting antidepressant effect, relief from existential distress, altered perception of pain
LSD	100–200 μg (oral)	Clinical or therapeutic setting with supervision	Preparatory session(s), 6–12 hour dosing session, integration afterward	Reduced death anxiety, spiritual experiences, emotional release, ego-dissolution
MDMA	75–125 mg (oral)	Therapeutic setting, often with music	1–3 sessions (6–8 hours) with preparatory and integration sessions	Process trauma, improve emotional connection with self/others, reduce fear and anxiety near end of life
Ayahuasca (DMT + MAOI)	Variable brew (2–5 ml/kg of decoction, potency varies)	Ceremonial / supervised retreat	1–2 ceremonies, often overnight, followed by integration sessions	Spiritual insight, confrontation of mortality, emotional release, mystical experiences
Peyote / San Pedro (Mescaline)	200–400 mg mescaline equivalent	Ceremonial / clinical setting	1–2 sessions (6–10 hours), preparatory and integration sessions	Connection to ancestors, spiritual insight, existential peace, anxiety relief

Key Notes on Protocols

1. Preparation is Critical: Patients usually undergo at least 1–2 preparatory sessions to set intentions, discuss fears, and establish trust with facilitators.
2. Integration: After the dosing session, integration therapy is conducted to help patients process and apply insights into daily life and end-of-life planning.
3. Therapeutic Support: Sessions are always supervised by trained therapists or guides to manage challenging experiences or psychological distress.
4. Medical Monitoring: Especially for IV ketamine or high-dose psychedelics, vital signs and mental state are closely monitored.
5. Legal / Regulatory Compliance: Protocols are adapted to the legal status of substances in the patient’s location.

If you want, I can make an even more detailed table that includes session timelines, music/ritual guidance, and integration techniques, which would basically function as a “ready-to-follow clinical guide” for end-of-life psychedelic therapy.

Do you want me to do that?

A