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Here’s a more detailed protocol table for psychedelic-assisted end-of-life therapy, integrating session timelines, preparation, music/ritual guidance, and integration techniques. This is based on clinical research and therapeutic practice:
|
Substance |
Dose / Administration |
Preparation |
Dosing Session |
Support & Environment |
Integration |
Typical Timeline |
|
Psilocybin |
20–30 mg oral (~0.3–0.5 mg/kg) |
1–2 preparatory sessions (1–2 hours each), discuss fears, intentions, prior psychological assessment |
6–8 hours; patient lies down with eyeshades, music playlist, optional guided imagery |
2 therapists present; safe, comfortable room; supportive communication |
1–2 post-session integration sessions (1–2 hours each) to discuss insights, fears, and end-of-life acceptance |
Week 1: prep; Week 2: dosing; Week 3–4: integration |
|
Ketamine |
0.5–1 mg/kg IV or 50–100 mg IM/sub-lingual |
Assessment for cardiac/mental health; intention-setting; brief mindfulness exercise |
40–60 minutes; patient monitored in reclining chair or bed |
Medical monitoring of BP, HR, O2; therapist present for guidance |
Integration session within 1–3 days; journaling, mindfulness, reflection |
1–5 sessions over 1–3 weeks depending on response |
|
LSD |
100–200 μg oral |
1–2 preparatory sessions; psychological assessment; grounding exercises |
6–12 hours; eyeshades, music, therapist support; optional guided meditations |
Comfortable, private room; at least 2 trained facilitators; emergency protocols in place |
Integration session(s) 1–3 days later; discussion of mystical experience, emotional release, acceptance of mortality |
Prep: 1–2 weeks; dosing: 1 day; integration: 2–3 days post-session |
|
MDMA |
75–125 mg oral |
1–2 prep sessions: trauma review, intention setting, coping strategies |
6–8 hours; therapist-guided; supportive music; optional gentle touch |
Two therapists present; patient encouraged to focus on emotional processing; safe, private setting |
Integration session 1–3 days post-dose; reinforce emotional breakthroughs, relational repair |
Prep: 1–2 weeks; dosing: 1 day; integration: 1–2 days post-session |
|
Ayahuasca (DMT + MAOI) |
2–5 ml/kg decoction, potency varies |
Pre-ceremony diet & mental preparation; intention setting; spiritual guidance |
4–8 hours; ceremonial space; guided by experienced shaman or facilitator; chanting, singing, ritual tools |
Supervised; attention to vomiting/purging; safe environment for introspection |
Integration session(s) 1–3 days later; journaling, discussion, spiritual counseling |
Prep: 1–3 days; ceremony: overnight; integration: 1–3 days after |
|
Peyote / San Pedro (Mescaline) |
200–400 mg mescaline equivalent |
Preparatory counseling; spiritual/ancestral intention; fasting or dietary guidance |
6–10 hours; ceremonial setting; singing/ritual, guided reflection |
Facilitator or shaman present; safe space for emotional release |
Integration 1–3 days later; processing visions, ancestral connections, death acceptance |
Prep: 1–2 days; dosing: 1 day; integration: 1–3 days after |
Additional Protocol Details
- Music & Ritual Guidance:
- Carefully curated playlists help guide emotional peaks and valleys.
- Rituals may include breathwork, chanting, or gentle touch depending on substance and tradition.
- Integration Techniques:
- Journaling, drawing, or storytelling to consolidate insights.
- Mindfulness or meditation exercises to reinforce acceptance and presence.
- Conversations with loved ones to repair relationships or express gratitude.
- Safety Measures:
- Vital signs monitored for ketamine or high-dose psychedelics.
- Emergency medications or protocols in place for rare adverse reactions.
- Psychological support always available during challenging experiences.
- Customization:
- Each patient’s dosage, session length, and integration plan are tailored to health status, mental state, and spiritual beliefs.
If you want, I can create a visual “flowchart-style protocol” showing the full week-by-week sequence from preparation to integration—essentially a ready-to-use clinical roadmap for end-of-life psychedelic therapy.
Do you want me to make that?
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