Friday, 18 July 2025

NT SHIFT CARCINOGEN

 A

It looks like you're referring to an article or study titled "Circadian Disruption: The Hidden Cancer Link?" by Maria Weiss, dated July 16, 2025.

Since you haven’t provided the full text, here’s a general overview of what such a topic likely covers:


Circadian Disruption and Cancer: What’s the Link?

  • Circadian rhythms are 24-hour biological cycles that regulate sleep, metabolism, hormone production, and other essential functions.

  • These rhythms are controlled by a "biological clock" in the brain (specifically, the suprachiasmatic nucleus in the hypothalamus) and are influenced by light exposure, especially sunlight.

🧬 How Disruption Occurs:

  • Shift work, jet lag, irregular sleep schedules, and excessive exposure to artificial light at night can all disrupt circadian rhythms.

  • This disruption affects the timing of cell repair, DNA replication, and hormone release, which can potentially contribute to the development and progression of cancer.

🔬 Evidence Linking Circadian Disruption to Cancer:

  • Studies show increased cancer risk (especially breast, prostate, and colorectal cancers) in long-term night-shift workers.

  • The World Health Organization (WHO) has classified night shift work as a probable carcinogen.

  • Melatonin suppression (caused by nighttime light exposure) may play a role, since melatonin has antioxidant and anti-cancer properties.

💡 Potential Solutions and Preventative Measures:

  • Limiting light exposure at night (especially blue light).

  • Maintaining regular sleep-wake cycles.

  • Designing work schedules to reduce chronic circadian disruption.

  • Research into chronotherapy — timing cancer treatments to circadian rhythms to improve effectiveness and reduce side effects.


If you have the full article or want a deeper dive into Maria Weiss’s take on this topic, feel free to share more text or ask specific questions.

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