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Yes — Michael Greger M.D. FACLM has indeed addressed whether supplements of Lutein (and the related Zeaxanthin) help brain function. His video titled *“Do Lutein Supplements Help with Brain Function?” explores the evidence. (NutritionFacts.org)
Here are the key take‑aways from his discussion:
✅ What the evidence looks like so far
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Lutein is abundant in dark green leafy vegetables, accumulates in the retina and also in brain tissue — and higher levels in the macula (eye) correlate with better cognitive test scores and neural integrity. (NutritionFacts.org)
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Some randomized controlled trials (RCTs) have shown that raising lutein/zeaxanthin intake (via foods or supplements) can lead to improvements in cognitive functions like spatial memory, reasoning ability, attention — at least in younger healthy adults and older adults. (NutritionFacts.org)
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However, in people with established cognitive decline (for example certain Alzheimer’s disease patients) the supplement studies didn’t show strong improvements in cognition — though vision sometimes improved. (NutritionFacts.org)
⚠️ Important caveats & Dr. Greger’s conclusions
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The majority of strong correlations are observational (higher lutein = better cognition) rather than proving cause → effect. Dr. Greger emphasises that observational data alone don’t prove that taking lutein leads to better brain outcomes. (NutritionFacts.org)
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Dietary sources (greens, leafy vegetables) may be more effective or at least more studied than just supplements. Dr. Greger raises the possibility that whole‑food contexts might offer advantages over isolated pigment pills. (NutritionFacts.org)
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Timing matters. If cognitive decline is already advanced, interventions may show less benefit — prevention and early intervention appear more promising. (NutritionFacts.org)
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He doesn’t make a blanket recommendation that everyone should take lutein supplements instead of increasing leafy greens — the emphasis remains on dietary intake.
📝 Practical take‑homes
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Incorporate more dark leafy greens (spinach, kale, collards etc) to boost lutein/zeaxanthin levels — this seems a low‑risk, food‑based strategy with good evidence.
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If considering lutein/zeaxanthin supplements specifically for cognition: the evidence is suggestive but not definitive — you might benefit, but it’s not guaranteed, especially in later stages of cognitive decline.
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Focus on overall diet, anti‑inflammatory lifestyle, brain‑healthy behaviours — not just a single supplement.
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If you already have a healthy diet, the marginal benefit of supplementation might be smaller; always check with a healthcare professional especially if you have a health condition or are on medications.
If you like, I can pull together all the clinical trials Dr Greger cites in that video (with doses, population, outcomes) so you can assess how strong the evidence is. Would you like that?
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