OMAS

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Opsoclonus–Myoclonus–Ataxia Syndrome (OMAS) — sometimes just called opsoclonus when referring to the eye movements — is a rare neurological disorder characterized by:

Core Features

1. Opsoclonus:
   Rapid, involuntary, chaotic, multidirectional eye movements (“dancing eyes”).

2. Myoclonus:
   Sudden, jerky muscle movements (“dancing feet”).

3. Ataxia:
   Problems with balance, coordination, or walking.

Other Possible Symptoms

• Irritability or behavioral changes

• Sleep disturbance

• Speech problems

• Cognitive or developmental regression (particularly in children)

Causes

OMAS is usually:

• Autoimmune or paraneoplastic
  – In children, often associated with neuroblastoma
  – In adults, may be linked to breast, lung, or ovarian tumors

• Post-infectious
  – Can follow viral infections

• Idiopathic
  – No clear cause found

Diagnosis

• Clinical exam (observing opsoclonus and ataxia)

• MRI brain (often normal)

• Immunologic tests

• Tumor screening (especially neuroblastoma in children)

Treatment

• Immunotherapy: steroids, IVIG, rituximab, ACTH

• Tumor treatment if a tumor is found

• Rehabilitation: physical, speech, and occupational therapy

If you’d like:

I can explain the condition in simpler terms, help with differential diagnoses, discuss treatment guidelines, or write a summary for medical notes.