Periportal tract brightness (also known as periportal echogenicity or periportal cuffing) is a sonographic finding seen on abdominal ultrasound, particularly around the portal triads in the liver.
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What It Looks Like on Ultrasound:
- Increased echogenicity (brightness) along the portal vein branches.
- Appears as linear bright streaks radiating from the portal vein into the liver parenchyma.
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Possible Causes of Periportal Tract Brightness:
|
Cause |
Mechanism |
|
Hepatitis (viral or toxic) |
Inflammatory edema or infiltration |
|
Congestive heart failure |
Hepatic venous congestion |
|
Lymphatic congestion |
Interstitial edema along portal triads |
|
Cholestasis / Obstructive jaundice |
Bile duct dilatation and periportal edema |
|
Liver transplant (post-op) |
Common post-transplant finding (fluid, inflammation) |
|
Cirrhosis / Fibrosis |
Sometimes seen in early stages |
|
Neonates |
Can be normal in newborns due to immature liver architecture |
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Clinical Context Is Essential:
Periportal brightness is non-specific — it’s a sign, not a diagnosis. It must be interpreted in light of:
- Liver function tests
- Signs of infection or heart failure
- Clinical symptoms (e.g., jaundice, ascites)
Let me know if you’d like help correlating this with lab results or a specific patient case.
The “starry sky” appearance of the liver on ultrasound (US) refers to a distinctive pattern where:
- The liver parenchyma appears hypoechoic (darker),
- While the portal venous walls and hepatic structures (which remain echogenic or bright) stand out like “stars” against the “sky” of the darkened liver background.
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Mechanism:
This appearance results from:
- Edema or inflammation of the liver → hypoechoic background
- Normal or prominent echogenicity of portal vein walls → bright dots/streaks
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Common Causes of Starry Sky Liver:
|
Condition |
Mechanism |
|
Acute hepatitis |
Hepatocellular edema |
|
Viral hepatitis (especially in children) |
Common classic cause |
|
Lymphoma (especially in children) |
Infiltrative disease |
|
Congestive hepatopathy |
Passive venous congestion |
|
Sepsis / shock liver |
Hepatic ischemia or inflammation |
|
Normal finding in children |
Due to less fatty infiltration and prominent vasculature |
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In Pediatrics:
- A starry sky liver is often seen in children with viral hepatitis, such as hepatitis A or E.
- May also be a transient normal variant in neonates.
✅ Summary:
The “starry sky” liver on ultrasound is a non-specific but important indicator of acute liver inflammation, most classically due to acute viral hepatitis, but also seen in sepsis, lymphoma, and congestive liver.
Would you like a visual example or comparison with CT/MRI findings?
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